Browsing by Subject "A61K 35/28"

Now showing items 1-13 of 13

    • Adult stem cells/progenitor cells and stem cell proteins for treatment of eye injuries and diseases 
      Prockop, Darwin J.; Oh, Joo Youn; Berkowitz, Barry; Roddy, Gavin W.; Rosa, Robert (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2018-10-23)
      The present invention encompasses methods and compositions for treating an ocular disease, disorder or condition in a mammal. The invention includes a population of mesenchymal stromal cells that possess anti-inflammatory, ...
    • Adult stem cells/progenitor cells and stem cell proteins for treatment of eye injuries and diseases 
      Prockop, Darwin J.; Oh, Joo Youn; Berkowitz, Barry; Roddy, Gavin W.; Rosa, Robert (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2015-06-23)
      The present invention encompasses methods and compositions for treating an ocular disease, disorder or condition in a mammal. The invention includes a population of mesenchymal stromal cells that possess anti-inflammatory, ...
    • Adult stem cells/progenitor cells and stem cell proteins for treatment of eye injuries and diseases 
      Prockop, Darwin J.; Oh, Joo Youn; Roddy, Gavin W.; Rosa, Robert; Berkowitz, Barry A. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2014-07-22)
      The present invention encompasses methods and compositions for treating an ocular disease, disorder or condition in a mammal. The invention includes a population of mesenchymal stromal cells that possess anti-inflammatory, ...
    • Adult stem cells/progenitor cells and stem cell proteins for treatment of eye injuries and diseases 
      Prockop, Darwin J.; Oh, Joo Youn; Berkowitz, Barry (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2017-01-17)
      The present invention encompasses methods and compositions for treating an ocular disease, disorder or condition in a mammal. The invention includes a population of mesenchymal stromal cells that possess anti-inflammatory, ...
    • Adult stem cells/progenitor cells and stem cell proteins for treatment of eye injuries and diseases 
      Prockop, Darwin J.; Oh, Joo Youn; Berkowitz, Barry; Roddy, Gavin W.; Rosa, Robert (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2017-08-15)
      The present invention encompasses methods and compositions for treating an ocular disease, disorder or condition in a mammal. The invention includes a population of mesenchymal stromal cells that possess anti-inflammatory, ...
    • Compositions of mesenchymal stem cells to regenerate bone 
      Gregory, Carl A.; Prockop, Darwin J. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2016-12-06)
      The present invention encompasses an osteogenic composition comprising mesenchymal stem cells pre-cultured in the presence of an agent that accelerates canonical Wnt signaling therein. Also, provided are osteogenic ...
    • Mesenchymal stem cells and supports for tissue regeneration, repair and reconstruction 
      Gregory, Carl A.; Krause, Ulf C.; Clough, Bret H. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2016-09-27)
      Materials and methods for preparing mesenchymal stem cells are described such that the mesenchymal stem cells remain for a longer period of time than would normally be found at a site of tissue healing. The mesenchymal ...
    • Mesenchymal stem cells derived from induced pluripotent stem cells 
      Prockop, Darwin J.; Lui, Fei; Zhao, Qingguo; Berkowitz, Barry A. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2019-07-16)
      "A method of producing mesenchymal stem cells from induced pluripotent stem cells in which induced pluripotent stem cells are cultured in the presence of a TGF-β inhibitor an in an atmosphere containing from about 7 vol. ...
    • Mineral-based nanoparticles for arthritis treatment 
      Gaharwar, Akhilesh K.; Carrow, James K. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2021-01-26)
      Aspects of the invention are directed to mineral-based nanoparticles comprising silicate nanoparticles that induce human mesenchymal stem cells (hMSCs) into a cartilage-lineage through the upregulation of cartilage-specific ...
    • Protein therapy for corneal inflammation, epithelial wound healing, and photoreceptor degeneration 
      Rosa, Robert; Roddy, Gavin W.; Prockop, Darwin J. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2014-06-24)
      The present invention encompasses methods, compositions, and devices for treating an ocular disease, disorder or condition in a mammal. The invention includes polypeptides that possess anti-inflammatory, anti-apoptotic, ...
    • Protein therapy for treatment of retinal diseases 
      Rosa, Robert; Roddy, Gavin W.; Prockop, Darwin J. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2015-07-28)
      The present invention encompasses methods, compositions, and devices for treating an ocular disease, disorder or condition in a mammal. The invention includes polypeptides that possess anti-inflammatory, anti-apoptotic, ...
    • Scalable production of standardized extracellular vesicles, extracellular vesicle preparations and uses thereof 
      Prockop, Darwin J.; Kim, Dong-Ki; Nishida, Hidetaka; Shetty, Askok K. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2021-11-02)
      Preparations comprising an enriched population of extracellular vesicles (nEVs) having a negatively charged surface, and that are CD81+ and CD9-, are provided. Improved processes and methods for producing an enriched ...
    • Stanniocalcin-1 (STC-1) therapy for treatment of retinal diseases 
      Rosa, Robert; Roddy, Gavin W.; Prockop, Darwin J. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2016-11-22)
      The present invention encompasses methods, compositions, and devices for treating an ocular disease, disorder or condition in a mammal. The invention includes polypeptides that possess anti-inflammatory, anti-apoptotic, ...